Naber, K. G. and Sörgel, F. and Kees, Frieder K. and Schumacher, H. and Metz, R. and Grobecker, H.
In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue.
The Journal of antimicrobial chemotherapy 22 Suppl D, pp. 199-207.
Fleroxacin is a new fluoroquinolone with a broad antibacterial spectrum and a serum half-life of about 8-12 h. Eighty percent of 400 isolates from complicated or hospital-acquired urinary tract infections were inhibited by a concentration of 1 mg/l and 95% by 4 mg/l. As with other quinolones, fleroxacin is less active in acid urine (pH 5.4) than in Mueller-Hinton broth (pH 7.4). In 12 healthy ...
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|Institutions:||Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann formerly Prof. Seifert)|
|Aged, 80 and over||MESH|
|Anti-Infective Agents/therapeutic use||MESH|
|Gram-Negative Bacteria/drug effects||MESH|
|Gram-Positive Bacteria/drug effects||MESH|
|Microbial Sensitivity Tests||MESH|
|Urinary Tract Infections/microbiology||MESH|
|Subjects:||600 Technology > 615 Pharmacy|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||30 Nov 2012 10:30|
|Last Modified:||13 Mar 2014 19:29|