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Involvement of pyrimidinoceptors in the regulation of cell functions by uridine and by uracil nucleotides

URN to cite this document:
Seifert, Roland ; Schultz, Günter
Date of publication of this fulltext: 24 Jan 2012 13:23


Uridine and uracil nucleotides are involved in the regulation of various cell functions. Here, Roland Seifert and Günter Schultz review the evidence that, rather than by binding to purinoceptors, pyrimidine nucleotides exert their effects by binding to distinct pyrimidinoceptors, which are coupled to pertussis toxin-sensitive G proteins in human phagocytes. However, many questions remain to be ...


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