Go to content
UR Home

Reversible activation of NADPH oxidase in membranes of HL-60 human leukemic cells

URN to cite this document:
urn:nbn:de:bvb:355-epub-232725
Seifert, Roland ; Schultz, Günter
[img]
Preview
PDF
(434kB)
Date of publication of this fulltext: 25 Jan 2012 13:49


Abstract

NADPH oxidase in membranes of undifferentiated and dimethylsulphoxide-differentiated HL-60 cells was activated by arachidonic acid (AA) in the presence of Mg2+ and a cytosolic cofactor (CF) found in differentiated HL-60 cells. Basal superoxide (O2-) formation was enhanced several-fold by addition of the stable GTP-analogue, guanosine 5'-O-(3-thiotriphosphate) (GTP gamma S), prior to AA and was ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons