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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-232964
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.23296
Alternative Links zum Volltext:Pubmed
Zusammenfassung
Cyclosporin A (CsA) has been reported to inhibit phorbol myristate acetate (PMA)-induced superoxide anion (O2-) formation in human neutrophils and murine macrophages. We found that CsA inhibited O2- formation in HL-60 cells induced by PMA (30 nM) and phorbol dibutyrate (200 nM) with a half-maximal effect at 1 and 0.75 microM, respectively. One possible target of CsA action is protein kinase C ...
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