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Comparative investigations on the bioavailability of cefuroxime axetil

URN to cite this document:
urn:nbn:de:bvb:355-epub-268292
Kees, Frieder K. ; Lukassek, U. ; Naber, K. G. ; Grobecker, H.
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Date of publication of this fulltext: 29 Nov 2012 12:26


Abstract

In a three-way cross-over study the bioavailability of cefuroxime was determined in 12 healthy volunteers after oral administration of 250 mg as cefuroxime axetil (Elobact; CAS 64544-07-6) in a plain aqueous suspension and as tablets from different batches. The tablet formulations showed nearly identical pharmacokinetic parameters and were bioequivalent. The mean maximum serum concentration was ...

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