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Relative bioavailability of three cefixime formulations

Kees, Frieder K., Naber, K. G., Sigl, G., Ungethüm, W. and Grobecker, H. J. (1990) Relative bioavailability of three cefixime formulations. Arzneimittel-Forschung 40 (3), pp. 293-297.

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Abstract

Three galenic formulations of cefixime (tablet, syrup and dry suspension) containing 200 mg each were compared with respect to their relative bioavailability in twelve healthy volunteers. All three formulations showed reliable absorption. Mean peak plasma concentrations were reached after 3.3-3.5 h, mean terminal half lives were 2.9-3.1 h. 18-24% of the dose administered were recovered unchanged ...

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Item type:Article
Date:1990
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann, formerly Prof. Seifert)
Identification Number:
ValueType
2346538PubMed ID
Classification:
NotationType
Administration, OralMESH
AdultMESH
Biological AvailabilityMESH
CefiximeMESH
Cefotaxime/urineMESH
Dosage FormsMESH
FemaleMESH
GelsMESH
Half-LifeMESH
HumansMESH
Intestinal AbsorptionMESH
MaleMESH
PowdersMESH
TabletsMESH
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26832
Owner only: item control page

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