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Pharmakokinetik von Cefixim bei Probanden und ein Literaturvergleich mit neuen Ester Prodrug Cephalosporinen [Pharmacokinetics of cefixime in volunteers and a literature comparison with the new ester prodrug cephalosporins]

Kees, Frieder K. and Naber, K. G. (1990) Pharmakokinetik von Cefixim bei Probanden und ein Literaturvergleich mit neuen Ester Prodrug Cephalosporinen [Pharmacokinetics of cefixime in volunteers and a literature comparison with the new ester prodrug cephalosporins]. Infection 18 Suppl 3, S150-S154.

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Abstract

The pharmacokinetic parameters of cefixime were determined in healthy volunteers following oral administration of 200 mg cefixime as tablet, syrup and dry suspension, respectively. All three galenic formulations showed reliable absorption. Mean peak plasma concentrations amounted to 2.4-3.4 mg/l and were reached after 3.3-3.5 h. Mean terminal half-lives were 2.9-3.1 h. The mean areas under the ...

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Item type:Article
Date:1990
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann, formerly Prof. Seifert)
Identification Number:
ValueType
2079377PubMed ID
Classification:
NotationType
Administration, OralMESH
AdultMESH
Anti-Infective Agents/pharmacokineticsMESH
Biological AvailabilityMESH
CefiximeMESH
Cefotaxime/pharmacokineticsMESH
Cephalosporins/pharmacokineticsMESH
EstersMESH
FemaleMESH
Half-LifeMESH
HumansMESH
MaleMESH
Molecular StructureMESH
Prodrugs/pharmacokineticsMESH
SolutionsMESH
SuspensionsMESH
TabletsMESH
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26835
Owner only: item control page

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