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Cefotaxime and desacetyl cefotaxime in human bile

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Kees, Frieder K. ; Strehl, E. ; Dominiak, P. ; Grobecker, H. ; Seeger, K. ; Seidel, G. ; Neuhaus, B. ; Safrany, L.
Date of publication of this fulltext: 30 Nov 2012 07:20


Ten patients were injected with 2 g cefotaxime i. v. The antibacterial activity in the bile was measured by the agar diffusion test and the concentrations of cefotaxime and desacetyl cefotaxime were determined by high performance liquid chromatography. The values found allow the use of cefotaxime in infectious biliary diseases.

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