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PROCOS: Computational analysis of protein–protein complexes

Fink, Florian ; Hochrein, Jochen ; Wolowski, Vincent ; Merkl, Rainer ; Gronwald, Wolfram


One of the main challenges in protein-protein docking is a meaningful evaluation of the many putative solutions. Here we present a program (PROCOS) that calculates a probability-like measure to be native for a given complex. In contrast to scores often used for analyzing complex structures, the calculated probabilities offer the advantage of providing a fixed range of expected values. This will ...


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