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Dietl, Katrin ; Renner, Kathrin ; Dettmer, Katja ; Timischl, Birgit ; Eberhart, Karin ; Dorn, Christoph ; Hellerbrand, Claus ; Kastenberger, Michael ; Kunz-Schughart, Leoni A. ; Oefner, Peter J. ; Andreesen, Reinhard ; Gottfried, Eva ; Kreutz, Marina

Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes

Dietl, Katrin, Renner, Kathrin, Dettmer, Katja , Timischl, Birgit, Eberhart, Karin, Dorn, Christoph, Hellerbrand, Claus, Kastenberger, Michael, Kunz-Schughart, Leoni A., Oefner, Peter J. , Andreesen, Reinhard, Gottfried, Eva and Kreutz, Marina (2010) Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes. Journal of immunology 184 (3), pp. 1200-1209.

Date of publication of this fulltext: 13 Aug 2014 08:33
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Details

Item typeArticle
Journal or Publication TitleJournal of immunology
Publisher:AMER ASSOC IMMUNOLOGISTS
Place of Publication:BETHESDA
Volume:184
Number of Issue or Book Chapter:3
Page Range:pp. 1200-1209
Date2010
InstitutionsMedicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Medicine > Lehrstuhl für Innere Medizin I
Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identification Number
ValueType
20026743PubMed ID
10.4049/jimmunol.0902584DOI
Classification
NotationType
Acidosis, Lactic/metabolismMESH
Cell Line, TumorMESH
Cell Survival/immunologyMESH
Cells, CulturedMESH
Coculture TechniquesMESH
Energy Metabolism/immunologyMESH
Glycolysis/immunologyMESH
Growth Inhibitors/pharmacologyMESH
HumansMESH
Immunosuppressive Agents/toxicityMESH
Lactic Acid/toxicityMESH
Melanoma/secretionMESH
Monocytes/secretionMESH
Reactive Oxygen Species/metabolismMESH
Tumor Necrosis Factor-alpha/secretionMESH
KeywordsDENDRITIC CELL ACTIVATION; COLONY-STIMULATING FACTOR; NECROSIS-FACTOR-ALPHA; LACTATE TRANSPORT; UP-REGULATION; NITRIC-OXIDE; MACROPHAGES; HYPOXIA; MECHANISMS; EXPRESSION;
Dewey Decimal Classification600 Technology > 610 Medical sciences Medicine
500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
600 Technology > 615 Pharmacy
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgPartially
Item ID30636

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