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Active DNA demethylation in the mononuclear phagocyte system

Schmidhofer, Sandra (2016) Active DNA demethylation in the mononuclear phagocyte system. PhD, Universität Regensburg.

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Date of publication of this fulltext: 18 Mar 2016 13:29

Abstract (English)

DNA demethylation processes have been studied for many years and entered the focus of extensive research with the discovery of active demethylation mechanisms (He et al., 2011; Ito et al., 2011; Iyer et al., 2009; Kriaucionis and Heintz, 2009; Tahiliani et al., 2009). These processes contribute to the regulation of cell type-specific gene expression patterns and the dynamics of other epigenetic ...

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Translation of the abstract (German)

Im Rahmen der Entdeckung aktiver DNA-Demethylierungsprozesse rückten DNA-Demethylierungsmechanismen erstmals in den Fokus der aktuellen Forschung (He et al., 2011; Ito et al., 2011; Iyer et al., 2009; Kriaucionis and Heintz, 2009; Tahiliani et al., 2009). Diese Mechanismen sind innerhalb der Zelle nicht nur an der Regulation der Genexpression, sondern auch an anderen epigenetischen Prozessen ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:18 March 2016
Referee:Prof. Dr. Michael Rehli
Date of exam:18 March 2015
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III
Keywords:DNA methylation, DNA demethylation, Epigenetics, Hematopoiesis, PU.1
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:32174
Owner only: item control page

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