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Active DNA demethylation in the mononuclear phagocyte system

URN to cite this document:
urn:nbn:de:bvb:355-epub-321747
Schmidhofer, Sandra
Date of publication of this fulltext: 18 Mar 2016 13:29


Abstract (English)

DNA demethylation processes have been studied for many years and entered the focus of extensive research with the discovery of active demethylation mechanisms (He et al., 2011; Ito et al., 2011; Iyer et al., 2009; Kriaucionis and Heintz, 2009; Tahiliani et al., 2009). These processes contribute to the regulation of cell type-specific gene expression patterns and the dynamics of other epigenetic ...

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Translation of the abstract (German)

Im Rahmen der Entdeckung aktiver DNA-Demethylierungsprozesse rückten DNA-Demethylierungsmechanismen erstmals in den Fokus der aktuellen Forschung (He et al., 2011; Ito et al., 2011; Iyer et al., 2009; Kriaucionis and Heintz, 2009; Tahiliani et al., 2009). Diese Mechanismen sind innerhalb der Zelle nicht nur an der Regulation der Genexpression, sondern auch an anderen epigenetischen Prozessen ...

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