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Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome

Weber, Daniela, Oefner, Peter J., Hiergeist, Andreas, Koestler, Josef, Gessner, Andre, Weber, Markus, Hahn, Joachim, Wolff, Daniel, Stämmler, Frank, Spang, Rainer, Herr, Wolfgang, Dettmer, Katja and Holler, Ernst (2015) Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome. Blood 126 (14), pp. 1723-1728.

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Date of publication of this fulltext: 12 Nov 2015 14:21

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Abstract

Urinary 3-IS levels predict outcome after ASCT and are associated with antibiotics and NOD2/CARD15 variants.Publisher’s Note: There is an Inside Blood Commentary on this article in this issue.Indole, which is produced from l-tryptophan by commensal bacteria expressing tryptophanase, not only is an important intercellular signal in microbial communities, but also modulates mucosal barrier function ...

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Item type:Article
Date:2015
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Medicine > Lehrstuhl für Orthopädie
Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Statistische Bioinformatik (Prof. Spang)
Identification Number:
ValueType
10.1182/blood-2015-04-638858DOI
Keywords:Urinary 3-IS levels predict outcome after ASCT and are associated with antibiotics and NOD2/CARD15 variants
Dewey Decimal Classification:000 Computer science, information & general works > 004 Computer science
500 Science > 540 Chemistry & allied sciences
500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:32750
Owner only: item control page

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