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Investigations on histamine and neuropeptide Y receptors by label-free and label-dependent methods

Lieb, Sebastian (2016) Investigations on histamine and neuropeptide Y receptors by label-free and label-dependent methods. PhD, Universität Regensburg.

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Date of publication of this fulltext: 19 Oct 2016 14:06

Abstract (English)

Label-free cell-based assays have been attracting growing attention in drug research. In this context, optical approaches based on evanescent electric fields (e.g. resonant waveguide grating, RWG; dynamic mass redistribution, DMR) and electrochemical impedance analysis (e. g. electric cell-substrate impedance sensing, ECIS) are the most widespread techniques. The aim of this doctoral thesis was ...

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Translation of the abstract (German)

Markierungsfreie zelluläre Assays sind in den letzten Jahren immer interessanter für die Arzneimittelforschung geworden. Von diesen neuen Analysetechniken sind die optischen- und impedanzbasierten Methoden am weitesten verbreitet. Ziel der Doktorarbeit war es, die optische (DMR; dynamic mass redistribution), sowie die impendanzbasierte markierungsfreie Analysemethode (ECIS, electric cell ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:19 October 2016
Referee:Prof. Dr. Armin Buschauer
Date of exam:14 October 2016
Institutions:Chemistry and Pharmacy > Institute of Pharmacy
Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Keywords:Label-free, DMR, RWG, SPR, ECIS
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:34738
Owner only: item control page

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