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Therapeutic Drug Monitoring of Antipsychotics - HPLC Analytical Method Development and Pharmaceutical Advices to the Ward Clinicians - For Successful Individualized Therapy

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Onuoha, Mary Remigius Agatha
Date of publication of this fulltext: 05 Dec 2016 11:49

Abstract (English)

This study aimed at the development of a new analytical procedure for the qualitative and quantitative determination of antipsychotics with low therapeutic concentrations and reference ranges such as melperone (MLP), benperidol (BPD), haloperidol (HLP), bromperidol (BRP), flupentixol (FLT) and zuclopenthixol (ZLT) in human serum, both individually as well as simultaneously. This objective was ...


Translation of the abstract (German)

Das Ziel dieser Arbeit ist die Entwicklung eines analytischen Verfahrens für die qualitative und quantitative Bestimmung von Antipsychotika mit niedrigen Konzentrationen und therapeutischen Referenzbereichen, wie Melperon (MLP), Benperidol (BPD), Haloperidol (HLP), Bromperidol (BRP), Flupentixol (FLT) und Zuclopenthixol (ZLT) in Humanserum, sodass die Substanzen sowohl einzeln als auch simultan ...


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