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Epimerisation of chiral hydroxylactones by short-chain dehydrogenases/reductases accounts for sex pheromone evolution in Nasonia

Ruther, Joachim, Hagström, Asa K., Brandstetter, Birgit, Hofferberth, John, Bruckmann, Astrid, Semmelmann, Florian, Fink, Michaela, Lowack, Helena, Laberer, Sabine, Niehuis, Oliver, Deutzmann, Rainer, Löfstedt, Christer and Sterner, Reinhard (2016) Epimerisation of chiral hydroxylactones by short-chain dehydrogenases/reductases accounts for sex pheromone evolution in Nasonia. Scientific Reports 6 (34697), pp. 1-13.

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Date of publication of this fulltext: 10 Feb 2017 11:14

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Other URL: http://www.nature.com/articles/srep34697


Abstract

Males of all species of the parasitic wasp genus Nasonia use (4R,5S)-5-hydroxy-4-decanolide (RS) as component of their sex pheromone while only N. vitripennis (Nv), employs additionally (4R,5R)-5-hydroxy-4-decanolide (RR). Three genes coding for the NAD+-dependent short-chain dehydrogenases/reductases (SDRs) NV10127, NV10128, and NV10129 are linked to the ability of Nv to produce RR. Here we show ...

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Item type:Article
Date:5 October 2016
Institutions:Biology, Preclinical Medicine > Institut für Zoologie > Chemische Ökologie (Prof. Dr. Joachim Ruther)
Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Reinhard Sterner
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I > Prof. Dr. Rainer Deutzmann
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1038/srep34697DOI
Article-ID: 34697Other
Keywords:Chemical ecology, Enzyme mechanisms
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:35156
Owner only: item control page

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