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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-356279
- DOI to cite this document:
- 10.5283/epub.35627
Abstract
Background: Treatment of arterial hypertension in patients with severe mental illnesses often results in polypharmacy, potentially leading to drug-drug interactions. The objective of the study was to analyse the in vivo inhibitory potential of two antihypertensive drugs, amlodipine and metoprolol on CYP2D6 catalysed 9-hydroxylation of risperidone (RIS). Methods: A therapeutic drug monitoring ...
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