Go to content
UR Home

Pharmacokinetic considerations in the treatment of hypertension in risperidone-medicated patients – thinking of clinically relevant CYP2D6 interactions

URN to cite this document:
urn:nbn:de:bvb:355-epub-356279
DOI to cite this document:
10.5283/epub.35627
Paulzen, M. ; Haen, Ekkehard ; Stegmann, Benedikt
[img]
Preview
License: Allianz- bzw. Nationallizenz
PDF - Published Version
(408kB)
Date of publication of this fulltext: 08 May 2017 13:10



Abstract

Background: Treatment of arterial hypertension in patients with severe mental illnesses often results in polypharmacy, potentially leading to drug-drug interactions. The objective of the study was to analyse the in vivo inhibitory potential of two antihypertensive drugs, amlodipine and metoprolol on CYP2D6 catalysed 9-hydroxylation of risperidone (RIS). Methods: A therapeutic drug monitoring ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons