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Structural transitions during large ribosomal subunit maturation analyzed by tethered nuclease structure probing in S. cerevisiae

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Milkereit, Philipp ; Pöll, Gisela ; Müller, Christian ; Bodden, Malena ; Teubl, Fabian ; Eichner, Norbert ; Lehmann, Gerhard ; Griesenbeck, Joachim ; Tschochner, Herbert
Date of publication of this fulltext: 16 Jan 2018 10:07


Yeast large ribosomal subunit (LSU) precursors are subject to substantial changes in protein composition during their maturation due to coordinated transient interactions with a large number of ribosome biogenesis factors and due to the assembly of ribosomal proteins. These compositional changes go along with stepwise processing of LSU rRNA precursors and with specific rRNA folding events, as ...


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