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Structural transitions during large ribosomal subunit maturation analyzed by tethered nuclease structure probing in S. cerevisiae

URN to cite this document:
urn:nbn:de:bvb:355-epub-365216
DOI to cite this document:
10.5283/epub.36521
Milkereit, Philipp ; Pöll, Gisela ; Müller, Christian ; Bodden, Malena ; Teubl, Fabian ; Eichner, Norbert ; Lehmann, Gerhard ; Griesenbeck, Joachim ; Tschochner, Herbert
Date of publication of this fulltext: 16 Jan 2018 10:07


Abstract

Yeast large ribosomal subunit (LSU) precursors are subject to substantial changes in protein composition during their maturation due to coordinated transient interactions with a large number of ribosome biogenesis factors and due to the assembly of ribosomal proteins. These compositional changes go along with stepwise processing of LSU rRNA precursors and with specific rRNA folding events, as ...

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