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Insights into the evolutionary conserved regulation of Rio ATPase activity

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Knüppel, Robert ; Christensen, Regitse H. ; Gray, Fiona C. ; Esser, Dominik ; Strauß, Daniela ; Medenbach, Jan ; Siebers, Bettina ; MacNeill, Stuart A. ; LaRonde, Nicole ; Ferreira-Cerca, Sébastien
Date of publication of this fulltext: 09 May 2018 12:22


Eukaryotic ribosome biogenesis is a complex dynamic process which requires the action of numerous ribosome assembly factors. Among them, the eukaryotic Rio protein family members (Rio1, Rio2 and Rio3) belong to an ancient conserved atypical protein kinase/ATPase family required for the maturation of the small ribosomal subunit (SSU). Recent structure-function analyses suggested an ...


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