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Antimicrobial and Hemolytic Studies of a Series of Polycations Bearing Quaternary Ammonium Moieties: Structural and Topological Effects

Mayr, Judith, Bachl, Jürgen, Schlossmann, Jens and Díaz Díaz, David (2017) Antimicrobial and Hemolytic Studies of a Series of Polycations Bearing Quaternary Ammonium Moieties: Structural and Topological Effects. International Journal of Molecular Sciences 18, p. 303.

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Date of publication of this fulltext: 05 Jul 2018 13:17

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Abstract

A series of polycations bearing quaternary ammonium moieties have shown antimicrobial activity against the Gram-negative bacterium Escherichia coli. Different polymer topologies governed by a disubstituted aromatic core as well as different diamine-based linkers were found to influence the antimicrobial properties. Moreover, the hemolytic activity against human red blood cells was measured and ...

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Item type:Article
Date:2017
Institutions:Chemistry and Pharmacy > Institute of Pharmacy
Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Prof. Dr. David Díaz Díaz
Identification Number:
ValueType
10.3390/ijms18020303DOI
Keywords:INFECTIOUS-DISEASES-SOCIETY; BAD BUGS; POLYMERS; ANTIBACTERIAL; DISINFECTANT; COPOLYMERS; HYDROGELS; PEPTIDES; AMERICA; IONENES; antimicrobial polymer; ionenes; polycations; quaternary ammonium; hemolysis; topomers
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37466
Owner only: item control page

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