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Photochromic peptidic NPY Y4-receptor ligands

Lachmann, Daniel, Konieczny, Adam, Keller, Max and König, Burkhard (2019) Photochromic peptidic NPY Y4-receptor ligands. Organic & Biomolecular Chemistry 17, pp. 2467-2478.

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Abstract

The neuropeptide Y (NPY) Y4 receptor is a G protein coupled receptor, which is targeted by pancreatic polypeptide, a homologue of NPY. Selective Y4R agonists were suggested as potential therapeutics for the treatment of obesity. Highly potent dimeric peptidic Y4R agonists, constituted of two pentapeptide moieties connected through an aliphatic linker, represent an interesting class of Y4R ...

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Item type:Article
Date:2019
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Projects:GRK 1910, Graduiertenkolleg "Medicinal Chemistry of Selective GPCR Ligands"
Identification Number:
ValueType
10.1039/C8OB03221ADOI
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38297
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