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Well-posedness of a Cahn–Hilliard system modelling tumour growth with chemotaxis and active transport
Garcke, Harald und Lam, Kei Fong
(2017)
Well-posedness of a Cahn–Hilliard system modelling tumour growth with chemotaxis and active transport.
European Journal of Applied Mathematics 28 (02), S. 284-316.
Veröffentlichungsdatum dieses Volltextes: 20 Mrz 2019 12:59
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.39156
Zusammenfassung
We consider a diffuse interface model for tumour growth consisting of a Cahn-Hilliard equation with source terms coupled to a reaction-diffusion equation. The coupled system of partial differential equations models a tumour growing in the presence of a nutrient species and surrounded by healthy tissue. The model also takes into account transport mechanisms such as chemotaxis and active transport. ...
We consider a diffuse interface model for tumour growth consisting of a Cahn-Hilliard equation with source terms coupled to a reaction-diffusion equation. The coupled system of partial differential equations models a tumour growing in the presence of a nutrient species and surrounded by healthy tissue. The model also takes into account transport mechanisms such as chemotaxis and active transport. We establish well-posedness results for the tumour model and a variant with a quasi-static nutrient. It will turn out that the presence of the source terms in the Cahn-Hilliard equation leads to new difficulties when one aims to derive a priori estimates. However, we are able to prove continuous dependence on initial and boundary data for the chemical potential and for the order parameter in strong norms.
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| Dokumentenart | Artikel | ||||
| Titel eines Journals oder einer Zeitschrift | European Journal of Applied Mathematics | ||||
| Verlag: | CAMBRIDGE UNIV PRESS | ||||
|---|---|---|---|---|---|
| Ort der Veröffentlichung: | NEW YORK | ||||
| Band: | 28 | ||||
| Nummer des Zeitschriftenheftes oder des Kapitels: | 02 | ||||
| Seitenbereich: | S. 284-316 | ||||
| Datum | 2017 | ||||
| Zusätzliche Informationen (Öffentlich) | OA-Komponente aus Allianzlizenz | ||||
| Institutionen | Mathematik > Prof. Dr. Harald Garcke | ||||
| Identifikationsnummer |
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| Stichwörter / Keywords | DIFFUSE INTERFACE MODEL; LONG-TIME BEHAVIOR; HELE-SHAW CELL; MIXTURE MODEL; RECONNECTION; SIMULATION; PINCHOFF; Tumour growth; phase field model; Cahn-Hilliard equation; reaction-diffusion equations; chemotaxis; weak solutions; well-posedness | ||||
| Dewey-Dezimal-Klassifikation | 500 Naturwissenschaften und Mathematik > 510 Mathematik | ||||
| Status | Veröffentlicht | ||||
| Begutachtet | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden | Ja | ||||
| URN der UB Regensburg | urn:nbn:de:bvb:355-epub-391568 | ||||
| Dokumenten-ID | 39156 |
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