Direkt zum Inhalt

Garcke, Harald ; Lam, Kei Fong

Well-posedness of a Cahn–Hilliard system modelling tumour growth with chemotaxis and active transport

Garcke, Harald und Lam, Kei Fong (2017) Well-posedness of a Cahn–Hilliard system modelling tumour growth with chemotaxis and active transport. European Journal of Applied Mathematics 28 (02), S. 284-316.

Veröffentlichungsdatum dieses Volltextes: 20 Mrz 2019 12:59
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.39156


Zusammenfassung

We consider a diffuse interface model for tumour growth consisting of a Cahn-Hilliard equation with source terms coupled to a reaction-diffusion equation. The coupled system of partial differential equations models a tumour growing in the presence of a nutrient species and surrounded by healthy tissue. The model also takes into account transport mechanisms such as chemotaxis and active transport. ...

We consider a diffuse interface model for tumour growth consisting of a Cahn-Hilliard equation with source terms coupled to a reaction-diffusion equation. The coupled system of partial differential equations models a tumour growing in the presence of a nutrient species and surrounded by healthy tissue. The model also takes into account transport mechanisms such as chemotaxis and active transport. We establish well-posedness results for the tumour model and a variant with a quasi-static nutrient. It will turn out that the presence of the source terms in the Cahn-Hilliard equation leads to new difficulties when one aims to derive a priori estimates. However, we are able to prove continuous dependence on initial and boundary data for the chemical potential and for the order parameter in strong norms.



Beteiligte Einrichtungen


Details

DokumentenartArtikel
Titel eines Journals oder einer ZeitschriftEuropean Journal of Applied Mathematics
Verlag:CAMBRIDGE UNIV PRESS
Ort der Veröffentlichung:NEW YORK
Band:28
Nummer des Zeitschriftenheftes oder des Kapitels:02
Seitenbereich:S. 284-316
Datum2017
Zusätzliche Informationen (Öffentlich)OA-Komponente aus Allianzlizenz
InstitutionenMathematik > Prof. Dr. Harald Garcke
Identifikationsnummer
WertTyp
10.1017/S0956792516000292DOI
Stichwörter / KeywordsDIFFUSE INTERFACE MODEL; LONG-TIME BEHAVIOR; HELE-SHAW CELL; MIXTURE MODEL; RECONNECTION; SIMULATION; PINCHOFF; Tumour growth; phase field model; Cahn-Hilliard equation; reaction-diffusion equations; chemotaxis; weak solutions; well-posedness
Dewey-Dezimal-Klassifikation500 Naturwissenschaften und Mathematik > 510 Mathematik
StatusVeröffentlicht
BegutachtetJa, diese Version wurde begutachtet
An der Universität Regensburg entstandenJa
URN der UB Regensburgurn:nbn:de:bvb:355-epub-391568
Dokumenten-ID39156

Bibliographische Daten exportieren

Nur für Besitzer und Autoren: Kontrollseite des Eintrags

nach oben