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Characterization of Muscle Glycogen Synthase and its Association with RNA in Sertoli Cells

URN to cite this document:
urn:nbn:de:bvb:355-epub-402357
DOI to cite this document:
10.5283/epub.40235
Maldonado, Rodrigo
Date of publication of this fulltext: 25 Jun 2019 11:44


Abstract (English)

The metabolism of Sertoli cells is highly active to maintain nutritional needs of germ cells. After glucose incorporation, only 1-3% is converted to glycogen suggesting low levels of glycogen synthase. Additionally, expression levels of muscular glycogen synthase (MGS), isoform present in these cells, do not correlate with the low levels of glycogen. Furthermore, MGS has a predicted Rossmann ...

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Translation of the abstract (German)

Der Stoffwechsel der Sertoli-Zellen ist hoch aktiv, um den Nährstoffbedarf der Keimzellen zu decken. Nach dem Einbau von Glucose werden nur 1-3% in Glykogen umgewandelt, was auf einen niedrigen Gehalt an Glykogensynthase hindeutet. Darüber hinaus korrelieren die Expressionsspiegel der in diesen Zellen vorhandenen Muskelglykogensynthase (MGS) -Isoform nicht mit den niedrigen Glykogenspiegeln. ...

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