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Protein Kinase G Is Involved in Acute but Not in Long-Term Regulation of Renin Secretion

Schramm, Andrea, Schweda, Frank, Sequeira-Lopez, Maria Luisa S., Hofmann, Franz, Sandner, Peter and Schlossmann, Jens (2019) Protein Kinase G Is Involved in Acute but Not in Long-Term Regulation of Renin Secretion. Frontiers in Pharmacology 2019 (10), p. 800.

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Date of publication of this fulltext: 25 Jul 2019 06:16

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Other URL: http://doi.org/10.3389/fphar.2019.00800


Abstract

Pharmacological inhibition of the renin–angiotensin–aldosterone system (RAAS) is, in combination with diuretics, the first-choice treatment for hypertension, although 10–20% of patients do not respond adequately. Next to the RAAS, the nitric oxide/cGMP/protein kinase G (PKG) system is the second fundamental blood pressure regulator. Whether both systems influence each other is not well-studied. ...

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Item type:Article
Date:18 July 2019
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann, formerly Prof. Seifert)
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3389/fphar.2019.00800DOI
Keywords:PKG, cGK, cGMP, sGC stimulation, renin, RAAS, juxtaglomerular apparatus
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40568
Owner only: item control page

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