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Effects of Intranasal Oxytocin on Thermal Pain in Healthy Men: A Randomized Functional Magnetic Resonance Imaging Study

Zunhammer, Matthias ; Geis, Sandra ; Busch, Volker ; Greenlee, Mark W. ; Eichhammer, Peter


Objective: Intranasal oxytocin has been shown to affect human social and emotional processing, but its potential to affect pain remains elusive. This randomized, placebo-controlled, double-blind, crossover trial investigated the effect of intranasal oxytocin on the perception and processing of noxious experimental heat in 36 healthy male volunteers. Methods: Thermal thresholds were determined ...


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