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18F-labelled triazolyl-linked argininamides targeting the neuropeptide Y Y1R for PET Imaging of mammary carcinoma

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Maschauer, Simone ; Ott, Julian J. ; Bernhardt, Günther ; Kuwert, Torsten ; Keller, Max ; Prante, Olaf
Date of publication of this fulltext: 09 Jan 2020 13:57


NeuropeptideYY(1) receptors (Y1R) have been found to be overexpressed in a number of different tumours, such as breast, ovarian or renal cell cancer. In mammary carcinoma the highY(1)R density together with its high incidence of 85% in primary human breast cancers and 100% in breast cancer derived lymph node metastases attracted special attention. Therefore, the aim of this study was the ...


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