| Lizenz: Creative Commons Namensnennung 4.0 International PDF - Veröffentlichte Version (1MB) |
- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-442124
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.44212
Zusammenfassung
In drug discovery, assays with proximal readout are of great importance to study target-specific effects of potential drug candidates. In the field of G protein-coupled receptors (GPCRs), the determination of GPCR-G protein interactions and G protein activation by means of radiolabeled GTP analogs ([S-35]GTP gamma S, [gamma-P-32]GTP) has widely been used for this purpose. Since we were repeatedly ...
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