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The cytokine IL‐17A as a marker of treatment resistance in major depressive disorder?

DOI to cite this document:
10.5283/epub.45413
Nothdurfter, Caroline ; Milenkovic, Vladimir M. ; Sarubin, Nina ; Hilbert, Sven ; Manook, André ; Weigl, Johannes ; Almeqbaali, Khalifa ; Wetzel, Christian H. ; Rupprecht, Rainer ; Baghai, Thomas C.



Abstract

Major depression is a complex disease and—among others, inflammation appears to play an important role in its pathophysiology. In this study, we investigated a broad range of cytokines in depressed patients. Plasma levels of interleukin (IL)‐12/ IL‐23p40, IL‐15, IL‐16, IL‐17A, IL‐1α, IL‐7, tumor necrosis factorβ and vascular endothelial growth factor were compared in 48 patients suffering from ...

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