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Exogenous testosterone and the monoamine-oxidase A polymorphism influence anger, aggression and neural responses to provocation in males

Wagels, Lisa ; Votinov, Mikhail ; Kellermann, Thilo ; Konzok, Julian ; Jung, Sonja ; Montag, Christian ; Schneider, Frank ; Eisert, Albrecht ; Beyer, Cordian ; Habel, Ute



Abstract

Testosterone and the monoamine oxidase-A (MAOA) polymorphism are potential neuromodulators for aggression. By acting on similar brain circuits, they might interactively influence human behavior. The current study investigates the causal role of testosterone on aggression-related brain activity and the potential interaction with the MAOA polymorphism. In a double-blind process, 93 healthy males ...

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