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Schertl, Sabine ; Hartmann, Rolf W. ; Batzl-Hartmann, Christine ; Bernhardt, Günther ; Spruß, Thilo ; Beckenlehner, Karin ; Koch, Marion ; Krauser, Rudolf ; Schlemmer, Richard ; Gust, Ronald ; Schönenberger, Helmut

[1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action I: antitumor activity due to the reduction of the endogenous estrogen level

Schertl, Sabine, Hartmann, Rolf W., Batzl-Hartmann, Christine, Bernhardt, Günther, Spruß, Thilo, Beckenlehner, Karin, Koch, Marion, Krauser, Rudolf, Schlemmer, Richard, Gust, Ronald and Schönenberger, Helmut (2004) [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action I: antitumor activity due to the reduction of the endogenous estrogen level. Archiv der Pharmazie 337 (6), pp. 335-348.

Date of publication of this fulltext: 05 Aug 2009 13:48
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Item typeArticle
Journal or Publication TitleArchiv der Pharmazie
Publisher:WILEY-V C H VERLAG GMBH
Place of Publication:WEINHEIM
Volume:337
Number of Issue or Book Chapter:6
Page Range:pp. 335-348
Date2004
InstitutionsChemistry and Pharmacy > Institute of Pharmacy
Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number
ValueType
15188223PubMed ID
10.1002/ardp.200300855DOI
Classification
NotationType
AnimalsMESH
Antineoplastic Agents, Hormonal/pharmacologyMESH
Apoptosis/drug effectsMESH
Cell Line, TumorMESH
Estrogens/biosynthesisMESH
FemaleMESH
HumansMESH
Mammary Neoplasms, Experimental/drug therapyMESH
MiceMESH
Neoplasms, Hormone-Dependent/drug therapyMESH
Organoplatinum Compounds/pharmacologyMESH
Ovary/drug effectsMESH
StereoisomerismMESH
Structure-Activity RelationshipMESH
Time FactorsMESH
Uterus/drug effectsMESH
KeywordsTUMOR INHIBITING PROPERTIES; IMMUNE-RESPONSE MODIFIER; PROGRAMMED CELL-DEATH; MOUSE MAMMARY-TUMOR; VARIABLE SUBSTITUENTS; 2-PHENYL RING; <1,2-BIS(2,6-DIHALO-3-HYDROXYPHENYL)ETHYLENEDIAMINE>PLATINUM(II) COMPLEXES; CYCLE ARREST; DNA-REPAIR; CISPLATIN; [1,2-bis(2,6-difluoro-3-hydroxyphenyl)ethylenediamine]platinum(II) complexes; anti-breast cancer activity; mode of action
Dewey Decimal Classification600 Technology > 615 Pharmacy
500 Science > 540 Chemistry & allied sciences
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
Item ID4836

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