Go to content
UR Home

Significance of the Protein Interface Configuration for Allostery in Imidazole Glycerol Phosphate Synthase

Kneuttinger, Andrea C. ; Rajendran, Chitra ; Simeth, Nadja A. ; Bruckmann, Astrid ; König, Burkhard ; Sterner, Reinhard


Imidazole glycerol phosphate synthase (ImGPS) from Thermotoga maritima is a model enzyme for studying allostery. The ImGPS complex consists of the cyclase subunit HisF and the glutaminase subunit HisH whose activity is stimulated by substrate binding to HisF in a V-type manner. To investigate the significance of a putative closing hinge motion at the cyclase:glutaminase interface for HisH ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons