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The Archaeal Proteome Project advances knowledge about archaeal cell biology through comprehensive proteomics

Schulze, Stefan ; Adams, Zachary ; Cerletti, Micaela ; De Castro, Rosana ; Ferreira-Cerca, Sébastien ; Fufezan, Christian ; Giménez, María Inés ; Hippler, Michael ; Jevtic, Zivojin ; Knüppel, Robert ; Legerme, Georgio ; Lenz, Christof ; Marchfelder, Anita ; Maupin-Furlow, Julie ; Paggi, Roberto A. ; Pfeiffer, Friedhelm ; Poetsch, Ansgar ; Urlaub, Henning ; Pohlschroder, Mechthild



Abstract

While many aspects of archaeal cell biology remain relatively unexplored, systems biology approaches like mass spectrometry (MS) based proteomics offer an opportunity for rapid advances. Unfortunately, the enormous amount of MS data generated often remains incompletely analyzed due to a lack of sophisticated bioinformatic tools and field-specific biological expertise for data interpretation. Here ...

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