A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia
Article
Sellmer, Andreas, Pilsl, Bernadette, Beyer, Mandy, Pongratz, Herwig, Wirth, Lukas, Elz, Sigurd, Dove, Stefan, Henninger, Sven Julian, Spiekermann, Karsten, Polzer, Harald, Klaeger, Susan, Kuster, Bernhard, Böhmer, Frank D., Fiebig, Heinz-Herbert, Krämer, Oliver H. and Mahboobi, Siavosh (2020) A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia. European Journal of Medicinal Chemistry 193, p. 112232.Alternative links to fulltext
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Details
| Item type | Article | ||||
| Journal or Publication Title | European Journal of Medicinal Chemistry | ||||
| Publisher | ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER | ||||
| Place of Publication | ISSY-LES-MOULINEAUX | ||||
| Volume | 193 | ||||
| Page Range | p. 112232 | ||||
| Date | 2020 | ||||
| Date of publication | 11 Oct 2021 12:51 | ||||
| Institutions | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry I (Prof. Elz) | ||||
| Identification Number |
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| Keywords | INTERNAL TANDEM DUPLICATION; THERAPEUTIC TARGET; F691L MUTATION; IN-VITRO; AML; RESISTANCE; CRENOLANIB; POTENT; CELLS; VALIDATION; FLT3; FLT3-ITD; FLT3 D835Y; Tyrosine kinase inhibitor; Acute myeloid leukemia | ||||
| Dewey Decimal Classification | 600 Technology > 615 Pharmacy | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 50072 |
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