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Szczepańska, Katarzyna ; Pockes, Steffen ; Podlewska, Sabina ; Höring, Carina ; Mika, Kamil ; Latacz, Gniewomir ; Bednarski, Marek ; Siwek, Agata ; Karcz, Tadeusz ; Nagl, Martin ; Bresinsky, Merlin ; Mönnich, Denise ; Seibel, Ulla ; Kuder, Kamil J. ; Kotańska, Magdalena ; Stark, Holger ; Elz, Sigurd ; Kieć-Kononowicz, Katarzyna

Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent

Article

Szczepańska, Katarzyna , Pockes, Steffen , Podlewska, Sabina, Höring, Carina, Mika, Kamil, Latacz, Gniewomir, Bednarski, Marek, Siwek, Agata , Karcz, Tadeusz, Nagl, Martin, Bresinsky, Merlin, Mönnich, Denise, Seibel, Ulla, Kuder, Kamil J. , Kotańska, Magdalena, Stark, Holger, Elz, Sigurd and Kieć-Kononowicz, Katarzyna (2021) Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent. European Journal of Medicinal Chemistry 213, p. 113041.



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Details

Item typeArticle
Journal or Publication TitleEuropean Journal of Medicinal Chemistry
PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
Place of PublicationISSY-LES-MOULINEAUX
Volume213
Page Rangep. 113041
Date2021
Date of publication02 Dec 2021 10:59
InstitutionsChemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry I (Prof. Elz)
Identification Number
ValueType
10.1016/j.ejmech.2020.113041DOI
KeywordsDRUG-LIKENESS; H3 RECEPTOR; BODY-WEIGHT; FOOD-INTAKE; IN-VITRO; DERIVATIVES; TARGET; IDALOPIRDINE; PHARMACOLOGY; INHIBITION; Histamine H-3 receptor; Non-imidazole histamine H3R ligands; Piperazine derivatives, Selective ligands; Molecular docking; Anti-obesity agents
Dewey Decimal Classification600 Technology > 615 Pharmacy
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgPartially
Item ID51104

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