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- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.51539
Zusammenfassung
Treatment of advanced melanoma with combined immune checkpoint inhibitor (ICI) therapy is complicated in up to 50% of cases by immune-related adverse events (irAE) that commonly include hepatitis, colitis and skin reactions. We previously reported that pre-therapy expansion of cytomegalovirus (CMV)-reactive CD4(+) effector memory T cells (T-EM) predicts ICI-related hepatitis in a subset of ...
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