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Tachycardiomyopathy entails a dysfunctional pattern of interrelated mitochondrial functions

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Paulus, Michael G. ; Renner, Kathrin ; Nickel, Alexander G. ; Brochhausen, Christoph ; Limm, Katharina ; Zügner, Elmar ; Baier, Maria J. ; Pabel, Steffen ; Wallner, Stefan ; Birner, Christoph ; Luchner, Andreas ; Magnes, Christoph ; Oefner, Peter J. ; Stark, Klaus J. ; Wagner, Stefan ; Maack, Christoph ; Maier, Lars S. ; Streckfuss-Bömeke, Katrin ; Sossalla, Samuel ; Dietl, Alexander
[img]License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 22 Sep 2022 04:57

This publication is part of the DEAL contract with Springer.


Tachycardiomyopathy is characterised by reversible left ventricular dysfunction, provoked by rapid ventricular rate. While the knowledge of mitochondria advanced in most cardiomyopathies, mitochondrial functions await elucidation in tachycardiomyopathy. Pacemakers were implanted in 61 rabbits. Tachypacing was performed with 330 bpm for 10 days (n = 11, early left ventricular dysfunction) or with ...


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