| Lizenz: Creative Commons Namensnennung 4.0 International PDF - Veröffentlichte Version (19MB) |
- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-535709
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.53570
Zusammenfassung
IntroductionGlutamine deficiency is a well-known feature of the tumor environment. Here we analyzed the impact of glutamine deprivation on human myeloid cell survival and function. MethodsDifferent types of myeloid cells were cultured in the absence or presence of glutamine and/or with L-methionine-S-sulfoximine (MSO), an irreversible glutamine synthetase (GS) inhibitor. GS expression was ...

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