Lizenz: Creative Commons Namensnennung 4.0 International PDF - Veröffentlichte Version (19MB) |
- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-535709
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.53570
Zusammenfassung
Introduction: Glutamine deficiency is a well-known feature of the tumor environment. Here we analyzed the impact of glutamine deprivation on human myeloid cell survival and function. Methods: Different types of myeloid cells were cultured in the absence or presence of glutamine and/or with L-methionine-S-sulfoximine (MSO), an irreversible glutamine synthetase (GS) inhibitor. GS expression was ...
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