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Bovine blood derived macrophages are unable to control replication under hypoxic conditions

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Mauermeir, Michael ; Ölke, Martha ; Hayek, Inaya ; Schulze-Luehrmann, Jan ; Dettmer, Katja ; Oefner, Peter J. ; Berens, Christian ; Menge, Christian ; Lührmann, Anja
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Date of publication of this fulltext: 23 May 2023 06:43


Background: Coxiella burnetii is a zoonotic pathogen, infecting humans, livestock, pets, birds and ticks. Domestic ruminants such as cattle, sheep, and goats are the main reservoir and major cause of human infection. Infected ruminants are usually asymptomatic, while in humans infection can cause significant disease. Human and bovine macrophages differ in their permissiveness for C. burnetii ...


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