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From sequence to function and back – High-throughput sequence-function mapping in synthetic biology

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Höllerer, Simon ; Desczyk, Charlotte ; Muro, Ricardo Farrera ; Jeschek, Markus
Date of publication of this fulltext: 02 Feb 2024 13:50


How does genetic sequence give rise to biological function? Answering this question is key to our understanding of life and the construction of synthetic biosystems that fight disease, resource scarcity and climate change. Unfortunately, the virtually infinite number of possible sequences and limitations in their functional characterization limit our current understanding of sequence-function ...


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