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Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants

Eap, C. B. ; Gründer, G. ; Baumann, P. ; Ansermot, N. ; Conca, A. ; Corruble, E. ; Crettol, S. ; Dahl, M. L. ; de Leon, J. ; Greiner, C. ; Howes, O. ; Kim, E. ; Lanzenberger, R. ; Meyer, J. H. ; Moessner, R. ; Mulder, H. ; Müller, D. J. ; Reis, M. ; Riederer, P. ; Ruhe, H. G. ; Spigset, O. ; Spina, E. ; Stegman, B. ; Steimer, W. ; Stingl, J. ; Suzen, S. ; Uchida, H. ; Unterecker, S. ; Vandenberghe, F. ; Hiemke, C.



Abstract

Objectives: More than 40 drugs are available to treat affective disorders. Individual selection of the optimal drug and dose is required to attain the highest possible efficacy and acceptable tolerability for every patient. Methods: This review, which includes more than 500 articles selected by 30 experts, combines relevant knowledge on studies investigating the pharmacokinetics, pharmacodynamics ...

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