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Dose-Related Reference Range as a Tool in Therapeutic Drug Monitoring

Haen, Ekkehard


Background: Therapeutic drug monitoring (TDM) aims to individualize drug therapy. This systematic review provides a state-of-the-art overview of the benefits of adding the dose-related reference range (DRR) as a second reference range to the set of tools used by TDM for measurement and evaluation. It discusses alternative pharmacokinetic approaches for individualization of drug therapy. Methods: ...


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