Polyisoprenylated acylphloroglucinols and a polyisoprenylated tetracyclic xanthone from the bark of Calophyllum thorelii

Nguyen, Le-Thu T. ; Nguyen, Hieu T. ; Barbič, Matej ; Brunner, Gabi ; Heilmann, Jörg ; Pham, Hung D. ; Nguyen, Duc M. ; Nguyen, Lien-Hoa D.

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Zusammenfassung

Two new polyisoprenylated acylphloroglucinols, thoreliones A and B, and a new polyisoprenylated tetracyclic xanthone, oxy-thorelione A, together with twelve known compounds, were isolated from the bark of Calophyllum thorelii. The new structures were determined using spectroscopic methods and chemical modification. The major compound thorelione A (1) showed moderate cytotoxic activity against ...