Mapping key amino acid residues for the epimerase efficiency and stereospecificity of the sex pheromone biosynthetic short-chain dehydrogenases/reductases of Nasonia

URN to cite this document:: urn:nbn:de:bvb:355-epub-382951
DOI to cite this document:: 10.5283/epub.38295

Semmelmann, Florian ; Hofferberth, John ; Ruther, Joachim

; Sterner, Reinhard

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Date of publication of this fulltext: 04 Feb 2019 10:42

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Abstract

Males of the parasitic wasp genus Nasonia use blends of chiral hydroxylactones as sex pheromones to attract conspecific females. Whereas all Nasonia species use a mixture of (4R,5S)-5-hydroxy-4-decanolide (RS) and 4-methylquinazoline (MQ) as sex pheromones, Nasonia vitripennis evolved (4R, 5R)-5-hydroxy-4-decanolide (RR) as an extra sex pheromone component. We recently identified and functionally ...