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Pharmaco-fMRI Challenges before and after short-term Treatment of Major Depression with Escitalopram, Mirtazapine, Agomelatine or Placebo and the Relation to the Hypothalamus-Pituitary-Adrenal-Axis Activity

URN to cite this document:
urn:nbn:de:bvb:355-epub-400848
DOI to cite this document:
10.5283/epub.40084
Mohammadi Jooyandeh, Somayeh
Date of publication of this fulltext: 18 Apr 2019 09:14


Abstract (English)

Background: Major Depressive Disorder (MDD) is a chronic stress related disorder characterized by depressed mood, by vegetative and cognitive symptoms. Imaging biomarkers may help to predict the impaired processing and regulation of emotions related to MDD and to antidepressant treatment response. Pharmaco neuroimaging and behavioral studies have shown that antidepressants can affect emotional ...

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Translation of the abstract (German)

Depressionen sind stress-assoziierte Erkrankungen, die durch eine depressive Verstimung sowie vegetative und kognitive Symptome gekennzeichnet sind. Bildgebungs-Biomarker können helfen, die beeinträchtigte Informationsverarbeitung und Emotionsregulation vorherzusagen, die mit Depressionen und dem Ansprechen auf eine antidepressive Behandlung assoziiert sind. Bildgebungs- und Verhaltensstudien ...

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