Go to content
UR Home

Cancer-associated cells release citrate to support tumour metastatic progression

URN to cite this document:
urn:nbn:de:bvb:355-epub-461727
DOI to cite this document:
10.5283/epub.46172
Drexler, Konstantin ; Schmidt, Katharina M. ; Jordan, Katrin ; Federlin, Marianne ; Milenkovic, Vladimir M. ; Liebisch, Gerhard ; Artati, Anna ; Schmidl, Christian ; Madej, Gregor ; Tokarz, Janina ; Cecil, Alexander ; Jagla, Wolfgang ; Haerteis, Silke ; Aung, Thiha ; Wagner, Christine ; Kolodziejczyk, Maria ; Heinke, Stefanie ; Stanton, Evan H. ; Schwertner, Barbara ; Riegel, Dania ; Wetzel, Christian H. ; Buchalla, Wolfgang ; Proescholdt, Martin ; Klein, Christoph A. ; Berneburg, Mark ; Schlitt, Hans J. ; Brabletz, Thomas ; Ziegler, Christine ; Parkinson, Eric K. ; Gaumann, Andreas ; Geissler, Edward K. ; Adamski, Jerzy ; Haferkamp, Sebastian ; Mycielska, Maria E.
[img]
Preview
License: Creative Commons Attribution 4.0
PDF - Published Version
(3MB)
Date of publication of this fulltext: 25 Jun 2021 19:14



Abstract

Citrate is important for lipid synthesis and epigenetic regulation in addition to ATP production. We have previously reported that cancer cells import extracellular citrate via the pmCiC transporter to support their metabolism. Here, we show for the first time that citrate is supplied to cancer by cancer-associated stroma (CAS) and also that citrate synthesis and release is one of the latter’s ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons