Go to content
UR Home

Overexpression of UHRF1 promotes silencing of tumor suppressor genes and predicts outcome in hepatoblastoma

Beck, Alexander ; Trippel, Franziska ; Wagner, Alexandra ; Joppien, Saskia ; Felle, Max ; Vokuhl, Christian ; Schwarzmayr, Thomas ; Strom, Tim M. ; von Schweinitz, Dietrich ; Längst, Gernot ; Kappler, Roland


Background: Hepatoblastoma (HB) is the most common liver tumor of childhood and occurs predominantly within the first 3 years of life. In accordance to its early manifestation, HB has been described to display an extremely low mutation rate. As substitute, epigenetic modifiers seem to play an exceptional role in its tumorigenesis, which holds promise to develop targeted therapies and establish ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons