| Lizenz: Creative Commons Namensnennung 4.0 International PDF - Veröffentlichte Version (817kB) |
- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-752521
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.75252
Zusammenfassung
A simple and fast HPLC-UV method is described for the simultaneous determination of total or free ceftazidime and avibactam in serum, which is suitable for therapeutic drug monitoring (TDM) or pharmacokinetic studies in man. Sufficient retention of the very polar avibactam was obtained by addition of tetrabutylammonium hydrogen sulfate (TBA) as ion pairing agent, thus allowing the determination ...

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