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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-26631
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.2663
Zusammenfassung
The calmodulin (CaM)-dependent adenylyl cyclase (AC) toxin from Bordetella pertussis (CyaA) substantially contributes to the pathogenesis of whooping cough. Thus, potent and selective CyaA inhibitors may be valuable drugs for prophylaxis of this disease. We examined the interactions of fluorescent 2',3'-N-methylanthraniloyl (MANT)-, anthraniloyl- and trinitrophenyl (TNP)-substituted nucleotides ...
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