| License: Creative Commons Attribution 4.0 Image (TIFF) Figure 6 (514kB) |
- URN to cite this document:
- urn:nbn:de:bvb:355-epub-315428
- DOI to cite this document:
- 10.5283/epub.31542
-
Mendoza, EzequielPreview
, Colomb, Julien , Raybak, Jürgen , Pflügler, Hans-Joachim, Zars, Troy , Scharff, Constance and Brembs, Björn
(2014)
Drosophila FoxP Mutants Are Deficient in Operant Self-Learning.
PLoS ONE 9 (6), e100648.
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Mendoza, Ezequiel, Colomb, Julien, Rybak, Jürgen, Pflüger, Hans-Joachim, Zars, Troy, Scharff, Constance and Brembs, Björn (2014) Conceptual architecture of operant feedback loops. [Image]Preview
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Mendoza, Ezequiel, Colomb, Julien, Rybak, Jürgen, Pflüger, Hans-Joachim, Zars, Troy, Scharff, Constance and Brembs, Björn (2014) Insertion mutants of the Drosophila FoxP gene affect isoform expression and flight performance. [Image]Preview
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Mendoza, Ezequiel, Colomb, Julien, Rybak, Jürgen, Pflüger, Hans-Joachim, Zars, Troy, Scharff, Constance and Brembs, Björn (2014) The mutant line FoxP³⁹⁵⁵ was impaired in operant self- but not world-learning. [Image]Preview
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Mendoza, Ezequiel, Colomb, Julien, Rybak, Jürgen, Pflüger, Hans-Joachim, Zars, Troy, Scharff, Constance and Brembs, Björn (2014) Deficiency ED5438 uncovers the FoxP³⁹⁵⁵ self-learning phenotype. [Image]Preview
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Mendoza, Ezequiel, Colomb, Julien, Rybak, Jürgen, Pflüger, Hans-Joachim, Zars, Troy, Scharff, Constance and Brembs, Björn (2014) Drosophila FoxP full length isoform B is required for operant self-learning. [Image]Preview
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Mendoza, Ezequiel, Colomb, Julien, Rybak, Jürgen, Pflüger, Hans-Joachim, Zars, Troy, Scharff, Constance and Brembs, Björn (2014) Subtle morphological alterations in the brains of FoxP³⁹⁵⁵ mutants. [Image] [Currently displayed]Preview
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![[img]](https://epub.uni-regensburg.de/style/images/fileicons/other.png)
Mendoza, Ezequiel, Colomb, Julien, Rybak, Jürgen, Pflüger, Hans-Joachim, Zars, Troy, Scharff, Constance and Brembs, Björn
(2014)
List of sequences used for the phylogenetic analysis of FoxP subfamily members.
[Dataset]
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Preview
Mendoza, Ezequiel, Colomb, Julien, Rybak, Jürgen, Pflüger, Hans-Joachim, Zars, Troy, Scharff, Constance and Brembs, Björn
(2014)
Drosophila FoxP Mutants Are Deficient in Operant Self-Learning.
[Image]
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| Item type: | Image | ||||
|---|---|---|---|---|---|
| Date: | 25 June 2014 | ||||
| Institutions: | Biology, Preclinical Medicine > Institut für Zoologie > Neurogenetik (Prof. Dr. Björn Brembs) | ||||
| Identification Number: |
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| Keywords: | anatomy, nervous system, Motor system, neuroanatomy, Evolutionary biology, genetics, Gene function, neuroscience, cognitive science, cognition, Animal cognition, Decision making, Behavioral neuroscience, Cognitive neuroscience, Learning and memory, Neuroethology, neuropsychology, psychology, behavior, habits, Verbal behavior, Experimental psychology, Zoology, Animal behavior, linguistics, speech, morphological, alterations, brains | ||||
| Dewey Decimal Classification: | 500 Science > 570 Life sciences 600 Technology > 610 Medical sciences Medicine | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Partially | ||||
| Item ID: | 31542 |
Abstract
a, Three-dimensional surface renderings of typical fly brains from wild type Canton S (a1) and FoxP³⁹⁵⁵ mutants (a2). PLOS ONE can only handle 3D PDF figures as part of the supplementary files. Hence, the 3D functionality for Figure 6 is available as Figure S3. Alternatively, a fully functional PDF will be hosted on BBs website. b, Quantitative volumetric analysis of eleven major neuropils (M – ...
Abstract
a, Three-dimensional surface renderings of typical fly brains from wild type Canton S (a1) and FoxP³⁹⁵⁵ mutants (a2). PLOS ONE can only handle 3D PDF figures as part of the supplementary files. Hence, the 3D functionality for Figure 6 is available as Figure S3. Alternatively, a fully functional PDF will be hosted on BBs website.
b, Quantitative volumetric analysis of eleven major neuropils (M – medulla, L – lobula, LP – lobula plate, MB – mushroom bodies, AL – antennal lobes, FB – fan-shaped body, OT – optic tubercle, EB – ellipsoid body, OG – optic glomeruli (purple in a), PB – protocerebral bridge, N – noduli) revealed a significant reduction in the volume of the optic glomeruli in FoxP³⁹⁵⁵ flies (Mann-Whitney U-Test, U = 2.0, p<0.002). The volume of the remaining neuropils (denoted PL – protocerebral lobes) did not differ significantly. Asterisk – significant difference with a Bonferroni-corrected level of p<0.004. Black stripes – median, boxes – 25–75% percentiles, whiskers – total range. Grey boxes indicate FoxP³⁹⁵⁵, white boxes Canton S.
c, Principal Components Analysis of the volumetric data. Plotted are the factor loadings of the individual flies on the two first components. Colored bars indicate means and standard errors (PC). Factor loadings are significantly different between Canton S and Foxp³⁹⁵⁵ for PC1 (Mann-Whitney U-Test, U = 52.0, p<0.04), but fail to reach significance for PC2. Number of brains analyzed: 7 (Canton S) and 9 (Foxp³⁹⁵⁵).
Metadata last modified: 29 Sep 2021 07:40
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