Go to content
UR Home

The sex-dependent role of the glucocorticoid receptor in depression: variations in the NR3C1 gene are associated with major depressive disorder in women but not in men

Sarubin, Nina ; Hilbert, Sven ; Naumann, Felix ; Zill, Peter ; Wimmer, Anna-Maria ; Nothdurfter, Caroline ; Rupprecht, Rainer ; Baghai, Thomas C. ; Bühner, Markus ; Schüle, Cornelius



Abstract

Genetic variations in the glucocorticoid receptor (GR) and the mineralocorticoid receptor (MR) have been associated with maladaptive stress responses and major depressive disorder (MDD). In a case-control study design, we examined whether single nucleotide polymorphisms (SNPs) and haploid genotype (haplotype) associations of MR gene NR3C2, GR gene NR3C1 and genes of GR chaperone molecules FK506 ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons