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Characterizing the nuclease accessibility of DNA in human cells to map higher order structures of chromatin

Schwartz, Uwe, Németh, Attila, Diermeier, Sarah, Exler, Josef H, Hansch, Stefan, Maldonado, Rodrigo, Heizinger, Leonhard, Merkl, Rainer and Längst, Gernot (2018) Characterizing the nuclease accessibility of DNA in human cells to map higher order structures of chromatin. Nucleic Acids Research 2018 (1), pp. 1-16.

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Date of publication of this fulltext: 29 Jan 2019 09:45

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Other URL: http://doi.org/10.1093/nar/gky1203, https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gky1203/5212010


Abstract

Packaging of DNA into chromatin regulates DNA accessibility and consequently all DNA-dependent processes. The nucleosome is the basic packaging unit of DNA forming arrays that are suggested, by biochemical studies, to fold hierarchically into ordered higher-order structures of chromatin. This organization has been recently questioned using microscopy techniques, proposing an irregular structure. ...

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Item type:Article
Date:28 November 2018
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Gernot Längst
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1093/nar/gky1203DOI
Keywords:Gene Regulation, Chromatin and Epigenetics
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38273
Owner only: item control page

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